{"id":3643,"date":"2025-02-19T14:38:14","date_gmt":"2025-02-19T13:38:14","guid":{"rendered":"https:\/\/ctgct.si\/?page_id=3643"},"modified":"2026-03-06T10:05:10","modified_gmt":"2026-03-06T09:05:10","slug":"publications","status":"publish","type":"page","link":"https:\/\/ctgct.si\/en\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

2026<\/h3>\n
\n

<\/i><\/span><\/i><\/span>Small RNAs, big potential: Engineering microRNA-based synthetic gene circuits <\/span><\/h3><\/a>\n
\n
Kundu, A., & Jerala, R. (2026). Current Opinion in Chemical Biology<\/i>, 90<\/i>, 102652. https:\/\/doi.org\/10.1016\/j.cbpa.2026.102652<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article>\n

\n

<\/i><\/span><\/i><\/span>Repurposing nuclear receptors for ligand-responsive liquid condensate formation and gene regulation<\/span><\/h3><\/a>\n
\n
Rihtar, E., Fink, T., Ivanovski, F., Koplan, E., & Jerala, R. (2026). . Nature Communications<\/i>. https:\/\/doi.org\/10.1038\/s41467-026-69099-4<\/a><\/p>\n

Check the blogpost<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article>\n

2025<\/h3>\n
\n

<\/i><\/span><\/i><\/span>Gene therapy of rare diseases as a milestone in medicine - overview of the field and report on initial experiences in Slovenia. <\/span><\/h3><\/a>\n
\n
Gro\u0161elj, U., Kav\u010di\u010d, M., Drole Torkar, A., Kafol, J., Lain\u0161\u010dek, D., Jerala, R., Sever, M., Zver, S., Ser\u0161a, G., \u010cema\u017ear, M., Strojan, P., Gro\u0161elj, A., \u017derjav Tan\u0161ek, M., Miro\u0161evi\u010d, \u0160., Ivan\u010dan, S., Prelog, T., Gosar, D., Ora\u017eem Mrak, J., Mlinari\u010d, M., \u2026 Osredkar, D. (2025). In Orphanet Journal of Rare Diseases <\/em>(Vol. 20, Issue 1). BioMed Central Ltd. https:\/\/doi.org\/10.1186\/s13023-025-03828-8<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article>\n

\n

<\/i><\/span><\/i><\/span>RNA trans-splicing to rescue \u03b2-catenin: A novel approach for treating CTNNB1-Haploinsufficiency disorder. <\/span><\/h3><\/a>\n
\n
Maruna, M., Su\u0161jan-Leite, P., Me\u0161ko, M., Miro\u0161evi\u010d, \u0160., & Jerala, R. (2025). Molecular Therapy Nucleic Acids<\/em>, 36<\/em>(3). https:\/\/doi.org\/10.1016\/j.omtn.2025.102680<\/a><\/p>\n

Check the blogpost<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article>\n

\n

<\/i><\/span><\/i><\/span>Genotypic, functional, and phenotypic characterization in CTNNB1 neurodevelopmental syndrome. <\/span><\/h3><\/a>\n
\n
<\/span> \u017dakelj, N., Gosar, D., Miro\u0161evi\u010d, \u0160., Sanders, S. J., Ljungdahl, A., Kohani, S., Huang, S., Leong, L. I., An, Y., Teo, M. J., Moultrie, F., Jerala, R., Lain\u0161\u010dek, D., Forstneri\u010d, V., Su\u0161jan, P., Lisowski, L., Perez-Iturralde, A., Mrak, J. O., Chan, H. Y. E., & Osredkar, D. (2025). Human Genetics and Genomics Advances<\/em>, 6<\/em>(4). https:\/\/doi.org\/10.1016\/j.xhgg.2025.100483<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article>\n

\n

<\/i><\/span><\/i><\/span>Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly. <\/span><\/h3><\/a>\n
\n
Bor\u0161i\u0107, E., Ramuta, T. \u017d., Orehek, S., Kreft, M. E., Geyer, M., Jerala, R., & Hafner-Bratkovi\u010d, I. (2025). Nature Communications <\/em>, 16<\/em>(1). https:\/\/doi.org\/10.1038\/s41467-025-60277-4<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Synthetic Biology for Designing Allostery and its Potential Biomedical Applications. <\/span><\/h3><\/a>\n
\n
<\/span>Plaper, T., \u0160tibler, U. K., & Jerala, R. (2025). . Journal of Molecular Biology<\/i>, 169225. https:\/\/doi.org\/10.1016\/j.jmb.2025.169225<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Ultrasound-responsive mammalian cell synthetic biology. <\/span><\/h3><\/a>\n
\n
Ivanovski, F., Jazbec, V., Varda, N., Jerala, R., & Ben\u010dina, M. (2025). IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control<\/i>, 1\u20131. https:\/\/doi.org\/10.1109\/TUFFC.2025.3570813<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Paving the way toward treatment solutions for CTNNB1 syndrome: a patient organization perspective<\/span><\/h3><\/a>\n
\n
Miro\u0161evi\u010d, \u0160., Khandelwal, S., Amerson, E., Parks, E., Parks, M., Cochran, L., Gonz\u00e1lez Hern\u00e1ndez, A., Ferraro, M., Lisowski, L., Perez-Iturralde, A., Chung, W., Jacob, M. H., \u017dakelj, N., Lain\u0161\u010dek, D., Forstneri\u010d, V., Su\u0161jan, P., Maruna, M., Jerala, R., & Osredkar, D. (2025). Therapeutic Advances in Rare Disease<\/em>,\u00a06<\/em>.\u00a0doi.org\/10.1177\/26330040251318355<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes<\/span><\/h3><\/a>\n
\n
Rihtar, E., Fink, T., Lebar, T., Lain\u0161\u010dek, D., Kolenc, \u017d., Polajnar, L. K., & Jerala, R. (2025). Cell Chemical Biology<\/em>.\u00a0doi.org\/10.1016\/j.chembiol.2025.01.007<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

2024<\/h3>\n

\n

<\/i><\/span><\/i><\/span>Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors<\/span><\/h3><\/a>\n
\n
Orehek, S., Ramuta, T. \u017d., Lain\u0161\u010dek, D., Malen\u0161ek, \u0160., \u0160ala, M., Ben\u010dina, M., Jerala, R., & Hafner-Bratkovi\u010d, I. (2024). \u00a0doi.org\/10.1038\/s41467-024-55083-3<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>CTGCT, Centre of Excellence for the Technologies of Gene and Cell Therapy: Collaborative translation of scientific discoveries into advanced treatments for neurological rare genetic diseases and cancer<\/span><\/h3><\/a>\n
\n
Presen, D. M., Lain\u0161\u010dek, D., Kinghorn, J., Sebestyen, Z., Kuball, J., Amini, L., Reinke, P., Fuchs, A., Jerala, R., & Ben\u010dina, M. (2024). Computational and Structural Biotechnology Journal<\/em>.\u00a0doi.org\/10.1016\/j.csbj.2024.11.051<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>MyD88 protein destabilization mitigates NF-\u03baB-dependent protection against macrophage apoptosis<\/span><\/h3><\/a>\n
\n
Lain\u0161\u010dek, D., Horvat, S., Dolinar, K., Ivanovski, F., Romih, R., Pirkmajer, S., Jerala, R., & Man\u010dek-Keber, M. (2024). Cell Communication and Signaling<\/em>,\u00a022<\/em>(1), 549.\u00a0doi.org\/10.1186\/s12964-024-01930-1<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Ultrasound-mediated spatial and temporal control of engineered cells in vivo<\/span><\/h3><\/a>\n
\n
Ivanovski, F., Me\u0161ko, M., Lebar, T., Rupnik, M., Lain\u0161\u010dek, D., Gradi\u0161ek, M., Jerala, R., & Ben\u010dina, M. (2024). doi.org\/10.1038\/s41467-024-51620-2<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Coupling of Spectrin Repeat Modules for the Assembly of Nanorods and Presentation of Protein Domains<\/span><\/h3><\/a>\n
\n
Mezgec, K., Snoj, J., Ul\u010dakar, L., Ljubeti\u010d, A., Tu\u0161ek \u017dnidari\u010d, M., \u0160karabot, M., & Jerala, R. (2024). ACS Nano<\/em>.\u00a0doi.org\/10.1021\/acsnano.4c07701<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>The art of designed coiled-coils for the regulation of mammalian cells<\/span><\/h3><\/a>\n
\n
Plaper, T., Rihtar, E., \u017deleznik Ramuta, T., Forstneri\u010d, V., Jazbec, V., Ivanovski, F., Ben\u010dina, M., & Jerala, R. (2024). Elsevier Ltd.\u00a0doi.org\/10.1016\/j.chembiol.2024.06.001<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Protein Gas Vesicles of Bacillus megaterium as Enhancers of Ultrasound-Induced Transcriptional Regulation<\/span><\/h3><\/a>\n
\n
Jazbec, V., Varda, N., \u0160prager, E., Me\u0161ko, M., Vidmar, S., Romih, R., Podobnik, M., Ke\u017ear, A., Jerala, R., & Ben\u010dina, M. (2024). ACS Nano<\/em>,\u00a018<\/em>(26), 16692\u201316700.\u00a0doi.org\/10.1021\/acsnano.4c01498<\/a><\/p>\nCheck the blogpost<\/a>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Mucoadhesive film for oral delivery of vaccines for protection of the respiratory tract<\/span><\/h3><\/a>\n
\n
Esih, H., Mezgec, K., Billmeier, M., Malen\u0161ek, \u0160., Ben\u010dina, M., Grilc, B., Vidmar, S., Ga\u0161perlin, M., Bele, M., Zidarn, M., Zupanc, T. L., Morgan, T., Jordan, I., Sandig, V., Schr\u00f6del, S., Thirion, C., Protzer, U., Wagner, R., Lain\u0161\u010dek, D., & Jerala, R. (2024). Journal of Controlled Release<\/em>,\u00a0371<\/em>, 179\u2013192.\u00a0doi.org\/10.1016\/j.jconrel.2024.05.041<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n

\n

<\/i><\/span><\/i><\/span>Designed allosteric protein logic<\/span><\/h3><\/a>\n
\n
Plaper, T., Merljak, E., Fink, T., Satler, T., Ljubeti\u010d, A., Lain\u0161\u010dek, D., Jazbec, V., Ben\u010dina, M., Stevanoska, S., D\u017eeroski, S., & Jerala, R. (2024). Cell Discovery<\/em>,\u00a010<\/em>(1).\u00a0doi.org\/10.1038\/s41421-023-00635-y<\/a><\/p>\n

<\/div>\n <\/div>\n <\/article><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

2026 2025 2024<\/p>\n","protected":false},"author":13,"featured_media":3759,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"iawp_total_views":151,"footnotes":""},"class_list":["post-3643","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nPublications - CTGCT<\/title>\n<meta name=\"description\" content=\"List of publications by the CTGCT\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ctgct.si\/en\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - CTGCT\" \/>\n<meta property=\"og:description\" content=\"List of publications by the CTGCT\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ctgct.si\/en\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"CTGCT\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-06T09:05:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1894\" \/>\n\t<meta property=\"og:image:height\" content=\"651\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ctgct.si\/en\/publications\/\",\"url\":\"https:\/\/ctgct.si\/en\/publications\/\",\"name\":\"Publications - CTGCT\",\"isPartOf\":{\"@id\":\"https:\/\/ctgct.si\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/ctgct.si\/en\/publications\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/ctgct.si\/en\/publications\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png\",\"datePublished\":\"2025-02-19T13:38:14+00:00\",\"dateModified\":\"2026-03-06T09:05:10+00:00\",\"description\":\"List of publications by the CTGCT\",\"breadcrumb\":{\"@id\":\"https:\/\/ctgct.si\/en\/publications\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/ctgct.si\/en\/publications\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/ctgct.si\/en\/publications\/#primaryimage\",\"url\":\"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png\",\"contentUrl\":\"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png\",\"width\":1894,\"height\":651,\"caption\":\"Construction of fluorescein inducible adapter CAR T cells\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/ctgct.si\/en\/publications\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/ctgct.si\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/ctgct.si\/#website\",\"url\":\"https:\/\/ctgct.si\/\",\"name\":\"CTGCT\",\"description\":\"\u010cas je za nove prilo\u017enosti\",\"publisher\":{\"@id\":\"https:\/\/ctgct.si\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/ctgct.si\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/ctgct.si\/#organization\",\"name\":\"CTGCT\",\"url\":\"https:\/\/ctgct.si\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/ctgct.si\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/ctgct.si\/wp-content\/uploads\/2022\/05\/logo-1.svg\",\"contentUrl\":\"https:\/\/ctgct.si\/wp-content\/uploads\/2022\/05\/logo-1.svg\",\"width\":156,\"height\":53,\"caption\":\"CTGCT\"},\"image\":{\"@id\":\"https:\/\/ctgct.si\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Publications - CTGCT","description":"List of publications by the CTGCT","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ctgct.si\/en\/publications\/","og_locale":"en_US","og_type":"article","og_title":"Publications - CTGCT","og_description":"List of publications by the CTGCT","og_url":"https:\/\/ctgct.si\/en\/publications\/","og_site_name":"CTGCT","article_modified_time":"2026-03-06T09:05:10+00:00","og_image":[{"width":1894,"height":651,"url":"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ctgct.si\/en\/publications\/","url":"https:\/\/ctgct.si\/en\/publications\/","name":"Publications - CTGCT","isPartOf":{"@id":"https:\/\/ctgct.si\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ctgct.si\/en\/publications\/#primaryimage"},"image":{"@id":"https:\/\/ctgct.si\/en\/publications\/#primaryimage"},"thumbnailUrl":"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png","datePublished":"2025-02-19T13:38:14+00:00","dateModified":"2026-03-06T09:05:10+00:00","description":"List of publications by the CTGCT","breadcrumb":{"@id":"https:\/\/ctgct.si\/en\/publications\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ctgct.si\/en\/publications\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ctgct.si\/en\/publications\/#primaryimage","url":"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png","contentUrl":"https:\/\/ctgct.si\/wp-content\/uploads\/2025\/02\/controlling-cells-with-chemical-switch.png","width":1894,"height":651,"caption":"Construction of fluorescein inducible adapter CAR T cells"},{"@type":"BreadcrumbList","@id":"https:\/\/ctgct.si\/en\/publications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ctgct.si\/en\/"},{"@type":"ListItem","position":2,"name":"Publications"}]},{"@type":"WebSite","@id":"https:\/\/ctgct.si\/#website","url":"https:\/\/ctgct.si\/","name":"CTGCT","description":"\u010cas je za nove prilo\u017enosti","publisher":{"@id":"https:\/\/ctgct.si\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ctgct.si\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/ctgct.si\/#organization","name":"CTGCT","url":"https:\/\/ctgct.si\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ctgct.si\/#\/schema\/logo\/image\/","url":"https:\/\/ctgct.si\/wp-content\/uploads\/2022\/05\/logo-1.svg","contentUrl":"https:\/\/ctgct.si\/wp-content\/uploads\/2022\/05\/logo-1.svg","width":156,"height":53,"caption":"CTGCT"},"image":{"@id":"https:\/\/ctgct.si\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/pages\/3643","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/comments?post=3643"}],"version-history":[{"count":10,"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/pages\/3643\/revisions"}],"predecessor-version":[{"id":5404,"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/pages\/3643\/revisions\/5404"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/media\/3759"}],"wp:attachment":[{"href":"https:\/\/ctgct.si\/en\/wp-json\/wp\/v2\/media?parent=3643"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}