The CTGCT is a unique project to develop the infrastructure associated with the development of gene and cell therapy technologies, working with international partners from prestigious institutions (UCL, UMC Utrecht, Charité Berlin, TU Dresden, University of Coimbra) that are key to the development of therapies for cancer and rare genetic diseases. The project addresses new treatment approaches, promotes international collaboration between researchers and brings together patients, clinicians and researchers. If you are ready to contribute your expertise to cutting-edge biomedical research, foster innovation and improve access to innovative advanced therapies, join us at CTGCT!
The CTGCT is growing, and we will soon start the process of demolishing a facility at the Kemijski Inštitut to build the new facility where we will GMP labs and animal facility to help us in our mission to translate research discoveries into therapies for cancer and rare diseases. If you would like to join the team and help us in our mission keep an eye on the career page of the Kemijski Inštitut as we will soon officially open calls for the following positions.
If you are interested contact us at CTGCT@ki.si with the name of the position you are interested on and a bit more information about you and your background.
GMP production and development expert
2 positions
Description of work and tasks
- Development of and setting up the production system and managing implementation in accordance with Slovenian, European and international legislation (EMA, FDA, ICH, Convention on Pharmaceutical Inspection);
- Preparation and review of GMP documentation;
- Ensuring that all activities are in line with current good practices (cGxP), and data integrity;
- Participation in the preparation of materials and/or preparation of proposals for R&D projects;
- Organisation of the assigned area;
- Preparation and support of controls and inspections;
- Participation in deviation investigations, preparation, support and coordination of corrective and preventive actions and follow-up of implementation;
- Training and coordinating the work of technical staff and transferring expertise to colleagues;
- Preparation of documentation, reports and studies on the work carried out;
- Preparation of technical reports, presentations, articles and other forms of dissemination or popularisation of development and technical work at home and abroad;
- Presentations of prepared materials to colleagues, the Head of Unit and, where appropriate, to external users;
- Communication with external bodies;
- Responsibility for personal and professional development;
- Other work as directed by supervisor, determined in accordance with discussion of objectives and performance indicators.
Our offer
- Duration of employment: Fixed term for the duration of the project, until 31.8.2029
- Probationary period: 4 months
- Working time: 40 hours/week
- Expected Qualifications: PhD; life sciences
- Alternative qualifications: PhD in pharmaceutical, biotechnology, biological, chemical, microbiological or other relevant life sciences
- Work experience: 4 years. Preferably work experience in production, bioprocess developmnet, sterile process development, quality assurance/quality control, or other professional quality experience.
Other:
Detailed description of duties and responsibilities: research and development work in the field of cell and gene therapy technology.
Preference will be given to candidates with a degree in biochemistry, biotechnology or pharmacy.
GMP production and development Assistant
2 positions
Description of works and tasks
- Participation in development and setting up the production system and managing its implementation in accordance with Slovenian, European and international legislation (EMA, FDA, ICH, Convention on Pharmaceutical Inspection);
- Preparation and review of GMP documentation;
- Conduct development, analyses and activities in accordance with current good practices (cGxP), and data integrity;
- Participation in the preparation of material and/or preparation of proposals for R&D projects;
- Organisation of assigned work tasks;
- Organisation and conducting maintenance of assigned work area;
- Participation and support in controls and inspections;
- Participation in deviation investigations, preparation, support and coordination of corrective and preventive actions and follow-up of implementation;
- Assisting in the training of technical staff and transferring expertise to colleagues;
- Contributing to the preparation of documentation, reports and studies on the work carried out;
- Contributing to the preparation of technical reports, presentations, articles and other forms of dissemination or popularisation of technical work at home and abroad;
- Presenting and/or contributing to the presentation of prepared materials to colleagues, the Head of Unit and, where appropriate, to external users;
- Responsibility for personal and professional development;
- Other work as directed by supervisor, determined in accordance with the discussion of objectives and performance indicators.
Our offer
- Duration of employment: Fixed term for the duration of the project, until 31.8.2029
- Probationary period: 4 months
- Working time: 40 hours/week
- Expected Qualifications: Master’s degree; Life sciences
- Alternative qualifications: Master’s degree; pharmaceutical, biotechnology, biological, chemical, microbiological or other relevant natural sciences
- Work experience: Preferably work experience in production, bioprocess development, sterile process development quality assurance/quality control, or other professional quality experience.
Other:
Detailed description of duties and responsibilities: research and development work in the field of cell and gene therapy technology.
Independent Researchers (PI)
3 Positions
KEY RESPONSIBILITIES
- organization and development of research activities in the chosen field,
- independent leadership and implementation of research in the field of cell and gene therapy technologies,
- leading a research group, knowledge transfer within the CTGCT team, and mentoring junior researchers,
- preparation of research proposals, project applications, and publications,
- monitoring approved projects and reporting,
- coordinating activities with partners in Slovenia and abroad.
REQUIREMENTS
- PhD in natural sciences or life sciences,
- at least 3 years of postdoctoral research experience,
- in-depth understanding of immunology, gene and cell therapy,
- preference will be given to candidates with experience in:
- development of vector/delivery systems (e.g., AAV, lentivirus, LNP),
- treatment of monogenetic diseases (e.g., CRISPR, RNA therapies, etc.),
- development/automation of bioprocesses for gene and cell therapies,
- experience in leading research projects and mentoring,
- ability to integrate knowledge, work in an interdisciplinary environment, and communicate effectively,
- eligibility to act as a principal investigator in Slovenia (ARIS or ERC).
WE OFFER
- fixed-term employment until 31 August 2029 (duration of the project), with the possibility of extension within the development of CTGCT,
- probation period: 4 months,
- full-time employment (40 hours/week),
- work in an internationally oriented, fast-growing research environment,
- access to state-of-the-art infrastructure and opportunities for translational work,
- collaboration with leading European research and clinical centers,
- support in applying for national and European research grants (e.g., ERC, Horizon Europe).
ABOUT US
CTGCT – Center for Gene and Cell Therapy Technologies is a new strategic unit of the National Institute of Chemistry (www.ki.si), focusing on the development of advanced technologies for the treatment of diseases where conventional medicine is insufficient. At the intersection of science, technology, and medicine, we are building a research environment where fundamental scientific findings lead to solutions for complex health challenges of the future.
Our activities are based on three pillars:
- development and optimization of technological platforms for cell and gene therapies (including delivery systems, genetic engineering, cell modification, etc.),
- establishment of conditions for therapeutic cell production in compliance with GMP (GMP-ready laboratories),
- translation of research solutions into clinical practice in cooperation with hospitals, research institutions, and industry.
We are connected with leading international institutions: UCL, UMC Utrecht, Charité Berlin, TU Dresden. We also collaborate with domestic clinical partners, enabling the direct application of research in a real medical environment.
We have access to modern research infrastructure: equipment for cell and molecular biology, flow cytometry, advanced microscopy, genetic analysis, laboratories for working with viral vectors and primary cells, and facilities under construction for the production of advanced therapies in compliance with GMP standards.
CONTACT US
If you are interested contact us at CTGCT@ki.si with the name of the position you are interested on and a bit more information about you and your background.