ArticlesATMPsManufacturing ProcessResearchUMCUtrechtRodrigo Ortiz 13 October 2026 Manufacturing Viral Vectors for Gene and Cell Therapies A gene therapy may begin with an elegant idea: deliver a genetic instruction to the right cells and change how they behave. Yet between that idea and a treatment lies an enormous manufacturing challenge. ... More
ArticlesPacientsGen TherapyResearchCTGCTRodrigo Ortiz 8 October 2026 The Growing Impact of Optogenetics What if scientists could control the activity of cells using nothing more than pulses of light? What sounds like science fiction has become one of the most influential technologies in modern biology. Earlier this ... More
ATMPsDrug DiscoveryRegulationResearchNICRodrigo Ortiz 6 October 2026 Advancing AAV Vector for Gene Therapies with URBAGEN For families affected by a rare and ultra-rare genetic disorder, the distance between a promising laboratory result and an accessible treatment can feel impossibly large. Developing a gene therapy requires much more than identifying ... More
ArticlesPacientsCell therapyResearchCTGCTNICRodrigo Ortiz 16 September 2026 From Skin Cells to Stem Cells: Reprogramming Cells to Study Disease Every cell in the human body contains essentially the same genetic instructions, yet a heart cell behaves very differently from a nerve or skin cell. For many years, scientists assumed that once a cell ... More
ArticlesPacientsGen TherapyResearchCTGCTNICRodrigo Ortiz 10 September 2026 Living Medicines: The Promise and Challenges of CAR-T Therapy Cancer treatment has undergone a remarkable transformation over the past decade. What if, instead of relying solely on drugs to attack tumors, we could reprogram a patient's own immune cells to seek out and ... More
ArticlesPacientsGen TherapyResearchCTGCTRodrigo Ortiz 27 August 2026 The Delivery Challenge of Genome Editing with CRISPR CRISPR technologies can rewrite a disease-causing DNA sequence, switch a gene off, correct a single genetic letter or even alter gene activity without changing the underlying DNA. Yet a genome editor can only work ... More
ArticlesResearchersGen TherapyResearchCTGCTNICRodrigo Ortiz 30 July 2026 Molecular Velcro: Using Coiled Coils to Deliver Genome Editors Beyond AAV Size Limits What if one of the biggest obstacles in gene therapy could be solved by borrowing a concept from everyday life? Just as Velcro joins two separate pieces together to create a strong and functional ... More
InterviewPacientsATMPsPre ClinicalResearchCTGCTNICRodrigo Ortiz 24 July 2026 Duško Lainšček interviewed by Svet24 How does a breakthrough gene therapy begin? What does it take to turn a scientific idea into a treatment that can reach a patient? In this interview, Duško Lainšček, researcher at the Institute of Chemistry ... More
EventsResearchersATMPsRegulationCTGCTRodrigo Ortiz 23 June 2026 Event Date: 9 June 2026 do: 9 June 2026 • CTGCT at GMP Symposium 2026: Contributing to ATMP Manufacturing Discussions The CTGCT was represented at the GMP Symposium 2026, held in Tuheljske Toplice, where leading experts gathered to exchange knowledge and practical experiences in GMP environments. As part of the scientific program, our head Dr. ... More
ArticlesPacientsATMPsCTGCTRodrigo Ortiz 19 June 2026 CTGCT Newsletter No. 4 Just as the summer is about to start your friend and colleague the CTGCT is publishing its latest newsletter with news and future events. Watch out! This is becoming a tradition every 6 months ... More
ArticlesResearchersGen TherapyResearchCTGCTRodrigo Ortiz 18 June 2026 Inside the GeneH Consortium Meeting and Symposium we organised On the 2nd of June 2026, the GeneH Consortium met together in Ljubljana for their yearly meeting and on the 3rd the consortium organized together with the Center for Functional Genomics and BioChips (CFGBC), ... More
EventsResearchersGen TherapyPre ClinicalResearchCTGCTNICRodrigo Ortiz 8 June 2026 Event Date: 11 May 2026 do: 15 May 2026 • CTGCT at ASGCT 2026 At the ASGCT 2026 Annual Meeting in Boston (May 11–15, 2026), held held in Boston, Massachusetts, USA, our colleague Dr. Duško Lainšček presented two pieces of work that reflect this translational reality. One of ... More