ArticlesCliniciansPacientsResearch 25 March 2026 Event Date: 2 March 2026 • 14:00 do: 2 March 2026 • 14:30 How AI is Helping Us Design the Proteins of the Future Imagine if we could design the "building blocks" of life just like we design a new house or a car. Instead of relying on what nature has given us through millions of years of ... More
ArticlesPacientsResearchersATMPsResearchCTGCTNICRodrigo Ortiz 3 March 2026 Remote-Controlling the Cell: The Future of Precision Medicine? Imagine if we could talk to our cells the same way we talk to a smart home device. We could tell a cell to start producing a specific medicine only when it’s needed or ... More
ArticlesCliniciansPacientsATMPsGen TherapyResearchTUDRodrigo Ortiz 12 February 2026 Molecular Surgery: How Base Editors are Rewriting the Future of Cancer Therapy Imagine being able to open the "instruction manual" of a human cell and fix a single typo that causes a life-threatening disease. This is no longer science fiction; it is the reality of base ... More
ArticlesPacientsResearchersCell therapyGMPResearchCharite BerlinRodrigo Ortiz 16 January 2026 Boosting Immunity After Transplantation: The Future of Automated T-Cell Therapy For patients undergoing a life-saving organ transplant, the road to recovery is often a delicate balancing act. While the new organ offers a second chance, the drugs needed to prevent the body from rejecting ... More
ArticlesPacientsResearchersATMPsGMPLaboratoryManufacturing ProcessPre ClinicalUMCUtrechtRodrigo Ortiz 9 December 2025 Bridging the Gap: The Role of GMP Simulation in ATMP Translation In recent decades, the medical toolbox has expanded dramatically. While traditional medicine relied on synthetic drugs (small molecules interacting with specific pathways) and later biologicals like antibodies, we have now entered the era of ... More
ArticlesCliniciansPacientsResearchersGen TherapyResearchCTGCTNICRodrigo Ortiz 25 September 2025 From Film Editing to RNA Editing: How RNA Trans-splicing Could Treat CTNNB1 Syndrome Imagine you're in a movie editing studio, trying to fix a film with some corrupted scenes. The film is vital, as it plays a crucial role in the development and function of an entire ... More
ArticlesCliniciansPacientsClinic studyRegulationCTGCTNICGregor Cuzak 16 July 2025 CTIS public portal – a great tool for finding and exploring clinical trials in Europe The Clinical Trials Information System (CTIS) public portal is a new European tool that allows anyone to access information about clinical trials taking place in the European Union (EU) and European Economic Area (EEA). ... More
ArticlesCliniciansPacientsResearchersGen TherapyResearchRodrigo Ortiz 5 June 2025 Unraveling the Mysteries of NLRP3: A Key Player in Inflammation In the complex world of cellular biology, proteins play a crucial role in maintaining our body's health and responding to threats. One such protein, NLRP3, is known for its ability to assemble the inflammasome ... More
ArticlesCliniciansPacientsResearchersCell therapyGen TherapyLaboratoryResearchCTGCTNICRodrigo Ortiz 3 June 2025 Harnessing Synthetic Biology for Innovative Medical Treatments In the world of synthetic biology, scientists are pushing the boundaries of what's possible by designing proteins that can be controlled in specific ways. This review written by Tjaša Plaper, Urška Knez Štibler and ... More
ArticlesCliniciansPacientsResearchersCell therapyResearchCTGCTNICRodrigo Ortiz 28 May 2025 How Ultrasound Can Control Cells, the Future of Medicine? Members of our team have already published work on sonogenetics (check our article breaking down that research here). We think this could have interesting applications in the future, since it overcomes the issue of ... More
ArticlesEventsCliniciansPacientsResearchersGen TherapyRaziskaveCTGCTNICRodrigo Ortiz 8 April 2025 Event Date: 21 March 2025 do: 21 March 2025 • CTGCT’s Role in the GeneH Project: Accelerating Gene Therapy Innovations We are thrilled to announce our participation in the GeneH consortium, an ambitious project led by the University of Coimbra, and their GeneT project, colead by the Kemijski Inštitut with the CTGCT project, aimed ... More
ArticlesCliniciansResearchersATMPsCell therapyGen TherapyManufacturing ProcessRegulationCTGCTUMCUtrechtRodrigo Ortiz 5 March 2025 Navigating Viral Vector Production for Gene Therapy This week we had the opportunity to listen to Ganesh Ramesh, a PhD candidate at the Viral Vector Production Center for Translation Immunology of UMC Utrecht, under the supervision of Dr. Zsolt Sebestyen. Here ... More
