ArticlesCliniciansPacientsResearchersGen TherapyResearchRodrigo Ortiz 5 June 2025 Unraveling the Mysteries of NLRP3: A Key Player in Inflammation In the complex world of cellular biology, proteins play a crucial role in maintaining our body's health and responding to threats. One such protein, NLRP3, is known for its ability to assemble the inflammasome ... More
ArticlesCliniciansPacientsResearchersCell therapyGen TherapyLaboratoryResearchCTGCTNICRodrigo Ortiz 3 June 2025 Harnessing Synthetic Biology for Innovative Medical Treatments In the world of synthetic biology, scientists are pushing the boundaries of what's possible by designing proteins that can be controlled in specific ways. This review written by Tjaša Plaper, Urška Knez Štibler and ... More
EventsCliniciansPacientsResearchersATMPsCell therapyGen TherapyBusiness ModelMarketaccessCTGCTNICGregor Cuzak 20 May 2025 Event Date: 1 May 2025 do: 31 May 2025 • Posters at Krakovski nasip – Ljubljanica embankment In May 2025, our Centre for the Technologies of Gene and Cell Therapy CTGCT) is participating in a poster exhibition on Krakovski nasip, as part of the Chemical Institute’s public presentation. More
ArticlesEventsCliniciansPacientsResearchersGen TherapyRaziskaveCTGCTNICRodrigo Ortiz 8 April 2025 Event Date: 21 March 2025 do: 21 March 2025 • CTGCT’s Role in the GeneH Project: Accelerating Gene Therapy Innovations We are thrilled to announce our participation in the GeneH consortium, an ambitious project led by the University of Coimbra, and their GeneT project, colead by the Kemijski Inštitut with the CTGCT project, aimed ... More
EventsCliniciansResearchersGen TherapyResearchCTGCTRodrigo Ortiz 12 March 2025 Event Date: 17 March 2025 • 14:00 do: 17 March 2025 • 15:00 Gene Therapy: Triumphs, Challenges, and Future Directions Lecture by Luis Pereira de Almeida on the 17th of March at the Kemijski Inštitut More
ArticlesCliniciansResearchersATMPsCell therapyGen TherapyManufacturing ProcessRegulationCTGCTUMCUtrechtRodrigo Ortiz 5 March 2025 Navigating Viral Vector Production for Gene Therapy This week we had the opportunity to listen to Ganesh Ramesh, a PhD candidate at the Viral Vector Production Center for Translation Immunology of UMC Utrecht, under the supervision of Dr. Zsolt Sebestyen. Here ... More
ArticlesPacientsATMPsCell therapyGen TherapyBusiness ModelEconomicsPre ClinicalResearchCTGCTNICRodrigo Ortiz 28 February 2025 How Patient Advocacy is Driving Breakthroughs to Treat CTNNB1 Syndrome Imagine a world where a child’s genetic disorder, once considered untreatable, is finally on a path toward real solutions. For families affected by the CTNNB1 syndrome, that future is becoming a reality thanks to ... More
ArticlesPacientsResearchersGen TherapyLaboratoryPre ClinicalResearchCTGCTNICRodrigo Ortiz 28 January 2025 The research on combining cytokines with pyroptosis is gaining widespread media coverage Research on combining cytokines and pyroptosis for cancer therapy by Slovenian scientists has gained significant media recognition, including TV features, articles, and the honor of being named "Names of the Week". More
ArticlesCliniciansPacientsCell therapyGen TherapyLaboratoryPre ClinicalResearchCTGCTNICRodrigo Ortiz 7 January 2025 Combining cytokines and pyroptosis, a promising weapon against cancer A recent study published in Nature Communications has unveiled a groundbreaking approach that combines the power of cytokines with a type of cell death called pyroptosis to boost the immune system's ability to fight ... More
ArticlesMedia ReleasesResearchersATMPsCell therapyGen TherapyResearchCharite BerlinCTGCTNICTUDUCLUMCUtrechtRodrigo Ortiz 6 December 2024 CTGCT’s Innovation Report on Gene and Cell Therapy We are pleased to share that our latest paper has been accepted for publication in the Computational and Structural Biotechnology Journal (CSBJ) More
ArticlesPacientsGen TherapyDrug DiscoveryLaboratoryResearchCTGCTNICRodrigo Ortiz 22 November 2024 MyD88 balances cell homeostasis by regulating immune response, mitochondrial function and cell death A recent study by researchers in the CTGCT investigates the role of the MyD88 protein, a key player in innate immune signaling pathways. More
ArticlesCliniciansResearchersATMPsCell therapyGen TherapyGLPGMPManufacturing ProcessPre ClinicalRegulationUCLRodrigo Ortiz 4 November 2024 Transforming Advanced Therapy Manufacturing: The Braintree Innovation Centre case study on the Braintree Manufacturing Innovation Centre (Braintree MIC), recently licensed by the MHRA. This state-of-the-art facility is revolutionizing the field of advanced therapy medicinal products (ATMPs) by providing cutting-edge infrastructure and expertise ... More
