ArticlesCliniciansPacientsCell therapyGen TherapyLaboratoryPre ClinicalResearchCTGCTNICRodrigo Ortiz 7 January 2025 Combining cytokines and pyroptosis, a promising weapon against cancer A recent study published in Nature Communications has unveiled a groundbreaking approach that combines the power of cytokines with a type of cell death called pyroptosis to boost the immune system's ability to fight ... More
LatestMedia ReleasesCliniciansPacientsResearchersResearchCTGCTRodrigo OrtizRodrigo Ortiz 11 December 2024 CTGCT Newsletter, 1st year in review Welcome to the first CTGCT Newsletter featuring a selection of the articles we're most proud of in the last year. More
ArticlesMedia ReleasesResearchersATMPsCell therapyGen TherapyResearchCharite BerlinCTGCTNICTUDUCLUMCUtrechtRodrigo Ortiz 6 December 2024 CTGCT’s Innovation Report on Gene and Cell Therapy We are pleased to share that our latest paper has been accepted for publication in the Computational and Structural Biotechnology Journal (CSBJ) More
ArticlesPacientsGen TherapyDrug DiscoveryLaboratoryResearchCTGCTNICRodrigo Ortiz 22 November 2024 MyD88 balances cell homeostasis by regulating immune response, mitochondrial function and cell death A recent study by researchers in the CTGCT investigates the role of the MyD88 protein, a key player in innate immune signaling pathways. More
EventsCliniciansPacientsResearchersATMPsCell therapyGen TherapyBusiness ModelDrug DiscoveryEconomicsInvestmentMarketaccessRegulationResearchCTGCTGregor Cuzak 12 September 2024 Event Date: 6 September 2024 • 09:00 do: 6 September 2024 • European Commission Hosts Sixth Regional HTA Event in Budapest The European Commission recently held its sixth regional event in Budapest, focusing on the upcoming Health Technology Assessment (HTA) regulation. Set to launch in January 2025, this new framework aims to streamline the evaluation ... More
ArticlesPacientsResearchersCell therapyGen TherapyResearchCTGCTNICRodrigo Ortiz 30 August 2024 Exciting news in Sonogenetics: A New Frontier for Deep Tissue Treatment Researchers have made a discovery that could change how we treat some diseases deep within the human body. This technique, known as sonogenetics, combines the power of ultrasound with genetically engineered cells to deliver ... More
EventsCliniciansResearchersGen TherapyDrug DiscoveryResearchCTGCTNICGregor Cuzak 17 July 2024 CTGCT about on/off switching of CAR-Ts at the EBMT 2024 Assoc. Prof Dr Mojca Benčina, head of the newly founded Slovenian Centre for the Technologies of Gene and Cell Therapy (CTGCT), gave a speech at the recent 50th Annual Meeting of the European Society ... More
CliniciansResearchersCell therapyGen TherapyGMPBusiness ModelClinic studyDrug DiscoveryEconomicsInvestmentLogisticsPre ClinicalResearchCTGCTNICUCLGregor Cuzak 17 July 2024 UCL ATMP Pipeline Our partner University College London (UCL) have produced a great short brochure (link) showing the strength and depth of their pipeline of ATMPs. They use a managed portfolio approach in which they support ~100 ... More
EventsCliniciansResearchersCell therapyGen TherapyGMPClinic studyMarketaccessRegulationResearchCharite BerlinCTGCTNICUMCUtrechtGregor Cuzak 1 July 2024 Panel Discussion on ATMP Regulation The CTGCT organised its first Panel Discussion on 29 May entitled: ATMP Regulation. The main takeaway from the very successful session was that the strong potential of the Slovenian ecosystem requires the will to ... More
InterviewResearchersDatamanagementDrug DiscoveryResearchCTGCTNICGregor Cuzak 27 June 2024 Interview with Shivang Khandewal – collaborator of NIC and CTNNB1 Originally from India, Shivang Khandelwal is presently engaged in advanced studies at the Hebrew University of Jerusalem. His primary research focus is on PCDH19 cluster epilepsy, a neurodevelopmental and neuropsychiatric disorder. He is deeply ... More
ArticlesCliniciansPacientsResearchersDrug DiscoveryMarketaccessRegulationResearchCTGCTGregor Cuzak 27 June 2024 Bespoke Gene Therapy Consortium – cooperation for rare disease therapies At the Bespoke Gene Therapy Consortium (BGTC, website), a consortium for the treatment of rare monogenetic diseases, they aim to treat neglected diseases with a very small number of patients with a focus solely ... More
EventsCliniciansPacientsResearchersGen TherapyGMPClinic studyDatamanagementDrug DiscoveryEthicalcommitteeInvestmentLaboratoryLogisticsManufacturing ProcessModalitetadelovanjazdravilaPharmacodynamicsPharmacokineticsPre ClinicalRaw MaterialRegulationResearchCTGCTNICGregor Cuzak 26 June 2024 Event Date: 14 June 2024 • 09:00 − 17:00 CTNNB1 Conference – One Year to Cure One year to cure is the goal shared by parents of children with the CTNNB1 Syndrome rare disease. Out of approximately 400 known cases worldwide, 82 families with children gathered at the conference in ... More