ArticlesATMPsManufacturing ProcessResearchUMCUtrechtRodrigo Ortiz 13 October 2026 Manufacturing Viral Vectors for Gene and Cell Therapies A gene therapy may begin with an elegant idea: deliver a genetic instruction to the right cells and change how they behave. Yet between that idea and a treatment lies an enormous manufacturing challenge. ... More
ArticlesPacientsGen TherapyResearchCTGCTRodrigo Ortiz 8 October 2026 The Growing Impact of Optogenetics What if scientists could control the activity of cells using nothing more than pulses of light? What sounds like science fiction has become one of the most influential technologies in modern biology. Earlier this ... More
ArticlesPacientsGen TherapyResearchCTGCTNICRodrigo Ortiz 10 September 2026 Living Medicines: The Promise and Challenges of CAR-T Therapy Cancer treatment has undergone a remarkable transformation over the past decade. What if, instead of relying solely on drugs to attack tumors, we could reprogram a patient's own immune cells to seek out and ... More
ArticlesResearchersGen TherapyResearchCTGCTNICRodrigo Ortiz 30 July 2026 Molecular Velcro: Using Coiled Coils to Deliver Genome Editors Beyond AAV Size Limits What if one of the biggest obstacles in gene therapy could be solved by borrowing a concept from everyday life? Just as Velcro joins two separate pieces together to create a strong and functional ... More
InterviewPacientsATMPsPre ClinicalResearchCTGCTNICRodrigo Ortiz 24 July 2026 Duško Lainšček interviewed by Svet24 How does a breakthrough gene therapy begin? What does it take to turn a scientific idea into a treatment that can reach a patient? In this interview, Duško Lainšček, researcher at the Institute of Chemistry ... More
ArticlesPacientsATMPsCTGCTRodrigo Ortiz 19 June 2026 CTGCT Newsletter No. 4 Just as the summer is about to start your friend and colleague the CTGCT is publishing its latest newsletter with news and future events. Watch out! This is becoming a tradition every 6 months ... More
ArticlesResearchersGen TherapyResearchCTGCTRodrigo Ortiz 18 June 2026 Inside the GeneH Consortium Meeting and Symposium we organised On the 2nd of June 2026, the GeneH Consortium met together in Ljubljana for their yearly meeting and on the 3rd the consortium organized together with the Center for Functional Genomics and BioChips (CFGBC), ... More
ArticlesPacientsATMPsPre ClinicalResearchCTGCTUCLRodrigo Ortiz 11 May 2026 Next-Generation T-Cell Therapies: From Laboratory Engineering to In Vivo Programming In our latest edition of the CTGCT Science Talks webinar series we had Dr. Thomas Fox, a clinician-scientist whose work bridges the gap between the clinical-laboratory interface working across Harvard Medical School and the ... More
LatestResearchersCell therapyResearchCTGCTNICRodrigo Ortiz 15 April 2026 New Project Grant Received: Sonogenetics as a central modulator of CAR-T function and lineage commitment As part of our efforts towards the sustainability of the CTGCT and with the goal in mind to develop new gene and cell therapies for cancer and rare diseases, our team members are applying ... More
LatestCliniciansPacientsResearchersCell therapyGen TherapyCTGCTRodrigo Ortiz 17 December 2025 CTGCT Newsletter No. 3 – Happy Holidays to everyone! As the year wraps up, we want to share our third official CTGCT newsletter, summarizing a period of great growth, both in our team size and our scientific impact! In the last six months, we ... More
EventsPacientsEconomicsCTGCTRodrigo Ortiz 12 December 2025 Event Date: 15 October 2025 do: 17 October 2025 • Building a Sustainable Future: CTGCT at the 4th Teaming Club Conference in Porto From October 15th to 17th, our colleague Vesna Merc joined colleagues and leaders from other Centres of Excellence across Europe for the 4th Teaming Club Conference. Hosted by BIOPOLIS, Biodiversity and Genetic Resources Research ... More
ArticlesPacientsResearchersATMPsGMPLaboratoryManufacturing ProcessPre ClinicalUMCUtrechtRodrigo Ortiz 9 December 2025 Bridging the Gap: The Role of GMP Simulation in ATMP Translation In recent decades, the medical toolbox has expanded dramatically. While traditional medicine relied on synthetic drugs (small molecules interacting with specific pathways) and later biologicals like antibodies, we have now entered the era of ... More